Overall information

FSDB ID	PP1E0010	Type	+1 frameshifting
Data	PREDICTED	Kingdom	eukaryota
Definition	Xenopus laevis mRNA for ornithine decarboxylase antizyme, complete cds. 997 bp mRNA linear VRT 08-JUN-2006
Resource	[1] Ichiba T, Matsufuji S, Miyazaki Y, Hayashi S. Biochim Biophys Acta. 1995 May 17;1262(1):83-6. [2] Ivanov IP, Matsufuji S, Murakami Y, Gesteland RF, Atkins JF. EMBO J. 2000 Apr 17;19(8):1907-17.
Nucleic acid sequence		D32141
Amino acid sequence
gene	oaz
CDS	Click for details join(66..239,241..717) /ribosomal_slippage /note="Translation needs frameshifting (Matsufuji et al. cited by Gesteland et al. (Science 1992 257 1640-1641). polyamine-dependent +1 frameshifting at nt240 possible another start codon at pos:147..149" /codon_start=1 /product="ornithine decarboxylase antizyme" /protein_id="BAA06867.1" /db_xref="GI:1655517" /translation="MVKSSLQRILNSHCFAREKEGNKRNDAMPLLSIPSSSESSRASF NCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNITEELTSNNR TRILNVQSSLTDGKQVSWRAVLNNNNLYIEIPSGTLPDGSKDSFAILLEYAEEQLQVD HVFICFHKNRDDRAMLLRTFRFLGFEIVIPGHPLVPKRPDACFMAYTFERDSSDED"

Graphical view

157 TGAGTATACCCAGTAGTAGTGAAAGTTCCAGGGCTTCTTTCAATTGCTGTAGTAACCTGGGTCCCGGGCCTCGGTGGTGT TCCTGA TGTC CCTCACCCACCCCTGAAGATCCCAGGTGGGCGAGGGAATAGTCAGAGGGATC
Stop codons	TGA (157),
Slippery sequence	TCCTGA (237 - 242)
Spacer	TGTC (4 nt)
Stimulatory structure	CCTCACCCACCCCTGAAGATCCCAGGTGGGCGAGGGAATAGTCAGAGGGATC (247 - 298)
	PREDICTED STRUCTURE Predicted by pknotsRG with the minimum energy option Visualized by PseudoViewer

Model

+1 eukaryote frameshift signal

FSFinder parameters

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(You can obtain the above result by running FSFinder with the sequence and parameter values. You may have to alternate frames to get the same result.)

Target gene

oaz gene

Sequence type

Patial genome

Direction

+ strand

Signal

Match sequences

spacer

nt

RNA structure

Stem Pseudoknot
- Stem1	<
- Stem2	<
- Loop1	<
- Loop2	<
- Loop3	<